RE: [ACEsthetics] Your teeth: The latest victim of toxic BPA exposure

Just able to get back online .

 

Well said, Todd. I was not endorsing the study or discounting it. Just passing it along so we would all be privy to what our patients might also see. This was in a report passed on by one of my very health conscious patients.

lisa

 

Lisa Marie Samaha, DDS, FAGD, PC

251 Nat Turner Blvd, Newport News, VA 23606
Phone: (757) 223-9270 Fax: (757) 223-9264
Email: SamahaDDS@PWDentalarts.com

Website:  www.PWDentalArts.com

 

From: tshewman [mailto:tshewman@insight.rr.com]
Sent: Thursday, June 27, 2013 11:11 PM
To: Dean Hutto
Cc: agoodman@agoodmandds.com; Rick Coker; Dr. Lisa Marie Samaha; gnr
Subject: Re: [ACEsthetics] Your teeth: The latest victim of toxic BPA exposure

 

It's no different than how hormones affect the rest of our bodies (we wouldn't be much without them). Screw up our hormones and we end up screwing up allot of our bodies, so teeth are not immune – the biggest take home from that study.

From: Dean Hutto

Sent: Thursday, June 27, 2013 10:36 PM

Subject: Re: [ACEsthetics] Your teeth: The latest victim of toxic BPA exposure

 

You two are way over most of our heads . But this is exactly why ACE is so valuable . I appreciate both of your insights. So... Thanks.  BTW.  I bet Tony understands everything about the function of the endocrine system in tooth development .... Just like me...  ;-)

Sent from my iPhone


On Jun 27, 2013, at 9:14 PM, Todd Shewman <tshewman@insight.rr.com> wrote:

Am interested in both. Especially the animal, skeletal and dentin chemistry, biochemistry, endocrine and signalling factors. Always helps to understand the animal selection process as well as the information that can be transferred to humans and what cannot. So far, I haven't seen the limitations in the work Lisa presented, only some support.  Precisely why I asked was because of the potential transfer of useful information (of which endocrine function is paramount).

 

Sent from mobile device



Ashley Goodman <agoodman@agoodmandds.com> wrote:

BTW my background also includes lab animal medicine and selection.  That includes which animals are best for different research protocols.  I was originally going to be going to vet school with that major, except that there was no such major then (Now there is).  They were concentrating on large animal medicine and I picked up scholarships in dental school; so here I am. 

There are a great many other variables besides endocrine and enamel chemistry that goes into an animal selection.  I'm still in the office running.  I know that it's about 7pm here but I'm trying to get out for the weekend and I haven't even packed yet.  I'm not going to do a course on lab animal selection here (Besides that was quite awhile ago and I've moved on).  There is a fairly decent course book put out by Purina, if you're interested in getting more info.

-------
 
Ash
 
------------------------------------
Ashley Goodman, DDS
8736 Lake Murray Blvd.#108
San Diego, Ca 92119
Phone:  619-697-6677
Fax:  619-697-6632
Email: agoodman@agoodmandds.com
Web:  www.agoodmandds.com
------------------------------------

On 6/27/2013 4:54 PM, tshewman wrote:

Am not aware of enamel chemistry being different. Any citations to demonstrate this?

Habelitz (See structure of Murine and Human Dentin) would tend to disagree as he cites mice as being the model mammal. He then did work comparing dentin between the two and to murine life (where he found a difference in murine).

Endocrine function being crucial to mineralization of many other things (like bone as well) in mice and humans, I would respectfully submit it is a crucial function.

 

Sent: Thursday, June 27, 2013 7:18 PM

Subject: Re: [ACEsthetics] Your teeth: The latest victim of toxic BPA exposure

 

As I recall from several decades ago, the diet composition wasn't equivalent enough to humans.  Saliva was distinctly different, along with flow.  Habits were too different.  Morphology of teeth and chewing habits different.  Enamel structure, thickness different, etc.  Too many differences to where endocrine function was a minor consideration among all the other variables.

We ended up going to rhesus monkeys where all we had to deal with were the political consequences and regular inspections by Indian representatives.

No time to go over email much today.  Really swamped and then out of town later. 

-------
 
Ash
 
------------------------------------
Ashley Goodman, DDS
8736 Lake Murray Blvd.#108
San Diego, Ca 92119
Phone:  619-697-6677
Fax:  619-697-6632
Email: agoodman@agoodmandds.com
Web:  www.agoodmandds.com
------------------------------------

On 6/27/2013 3:42 PM, tshewman wrote:

Please, correct me if I am wrong. As far as I know dentin is a composite mineralized tissue in mice and humans. Thus, requiring remineralization to maintain structural integrity. Remineralization requires proper endocrine function. What are the endocrine pathway differences that would limit the use of the research in mice compared to that in humans?

Sent: Thursday, June 27, 2013 6:04 PM

Subject: Re: [ACEsthetics] Your teeth: The latest victim of toxic BPA exposure

 

Rats are good research subjects, but in very limited ways.  For further research you go to rhesus monkeys , chimps, or pigs which be more relevant to human study (Depending on the application).

-------
 
Ash
 
------------------------------------
Ashley Goodman, DDS
8736 Lake Murray Blvd.#108
San Diego, Ca 92119
Phone:  619-697-6677
Fax:  619-697-6632
Email: agoodman@agoodmandds.com
Web:  www.agoodmandds.com
------------------------------------

On 6/27/2013 2:31 PM, Todd Shewman wrote:

Endocrine (hormone) disruption is known to affect mineralization of bone. This is simply an expansion on the other systems that is affected. Presumably those dealing with teeth would be interested in knowing the effects of the endocrine disruptors (e.g. bpa) as teeth require remineralization. Perhaps even looking at products used on patients, and if they contain such elements would be helpful.

Because of the known effects of BPA it is likely becoming more challenging to pass through the ethics stage to be trued in humans. It's not rocket science.

 

Sent from mobile device



Rick Coker mailto:riccoker@gmail.com wrote:

What if we care about rat nutrition and comfort? Ever tried to make a set of dentures for one of those? It is hell!

 

Rick

 

On Thu, Jun 27, 2013 at 10:50 AM, Ashley Goodman <agoodman@agoodmandds.com> wrote:

I did research on rats.  The tooth morphology is totally different, as is the diet, etc.  I don't understand the relevance to humans on this study.  It is enough to do further research (Different subjects, etc.), but not to take conclusions from broadly.

-------
 
Ash
 
------------------------------------
Ashley Goodman, DDS
8736 Lake Murray Blvd.#108
San Diego, Ca 92119
Phone:  619-697-6677
Fax:  619-697-6632
Email: agoodman@agoodmandds.com
Web:  www.agoodmandds.com
------------------------------------

On 6/27/2013 7:53 AM, Dr. Lisa Marie Samaha wrote:

Your teeth: The latest victim of toxic BPA exposurehttp://www.naturalnews.com/040963_teeth_BPA_tooth_enamel.html

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PWDental

Lisa Marie Samaha, DDS, FAGD, PC

251 Nat Turner Blvd, Newport News, VA 23606
Phone: (757) 223-9270 Fax: (757) 223-9264
Email: SamahaDDS@PWDentalarts.com

Website:  www.PWDentalArts.com

Â

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